Laboratory sterile homogenizer, also known as slapping homogenizer. It is suitable for homogenizing animal tissues and biological samples in the fields of food, medicine, cosmetics, clinical, molecular, toxin and bacterial detection, separating or extracting microorganisms contained in and on the surface of solid samples, and preparing representative samples. The instrument consists of an operation control manager, a stainless steel homogenization preparation box and a sterile homogenization bag. It has the characteristics of simple experimental operation, digital screen control, gentle homogenization, no pollution, no damage, no heating, no need for sterilization, no need to wash utensils, effectively preventing cross contamination, protecting the safety of operators, etc., meeting the experimental requirements of fast preparation, accurate results, good repeatability, etc.